Adults Only and Adult Friendly Resorts in Florida. Shoreline Island Resort. Show Prices. 1, reviews. Blanc Kara Boutique Hotel. Island Bay Resort. Kona Kai Resort, Gallery & Botanic . Positioned on 27 acres of lush gardens and feet of private waterfront, Cheeca Lodge & Spa is a luxury resort in Islamorada, Florida. It features a 9-hole par 3 golf course, on-site spa, and .